Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review

Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review
January 11, 2026

Systematic review of studies of laser therapy for inhibitory effects on peripheral nerve pain. In 13 of 18 human studies laser therapy was shown to slow conduction velocity and/or reduce the amplitude of compound action potentials.  Several mechanisms for the analgesic effects of laser therapy are also discussed.

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Published: Photomedicine and Laser Surgery. 2011; 29(6): 365-381. doi: 10.1089/pho.2010.2928

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